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The Science, Technology, Engineering, and Mathematics Talent Expansion Program (STEP) seeks to increase the number of students (U.S. citizens or permanent residents) receiving associate or baccalaureate degrees in established or emerging fields within science, technology, engineering, and mathematics (STEM). Type 1 proposals are solicited that provide for full implementation efforts at academic institutions. Type 2 proposals are solicited that support educational research projects on associate or baccalaureate degree attainment in STEM.

Program activities under the Type 1 STEP competition should be efforts aimed at implementing strategies that will lead to an increase in the number of students (United States citizens or permanent residents) obtaining STEM degrees at institutions with baccalaureate degree programs; or completing associate degrees in STEM fields or completing credits toward transfer to a baccalaureate degree program in STEM fields at community colleges. The goal of the project must be to increase the total graduation numbers of such students at the institution(s), and all STEP proposals must include specific numerical targets for these increases. If a project focuses efforts on only a subset of STEM fields, increases in those fields must not be at the expense of degrees in other STEM fields. Projects may focus on the retention and/or recruitment of undergraduate students into STEM fields. Projects should consider the importance of attention to broadening the participation of all sectors of the student population in STEM. Outreach efforts are appropriate only if the efforts can be expected to result in additional STEM majors and graduates at the submitting institution(s) within the grant period.

Program activities under the Type 2 STEP competition represent educational research on factors affecting associate or baccalaureate degree attainment in STEM. The results are expected to contribute to the knowledge base of scholarly research in education. Proposals of up to $500,000 annually (one-, two- or three-year awards) for projects should be based in a research design that incorporates appropriate and proven methodologies and strategies. The proposal should identify the research questions, and the results should provide convincing evidence of the relationship of the factor(s) (including departmental/institutional) studied to the issues of associate and/or baccalaureate degree attainment, and/or undergraduate access to STEM careers, and/or persistence to STEM graduate study. These educational research studies should reflect explicit cognizance of the broad variety of institutions of higher education, and should address the unique challenges and opportunities posed by that variety.

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The Fogarty International Center (FIC) and collaborating Institutes (NCI, NIEHS, NINDS, and NIBIB) are inviting applications for up to three years of support for the creation of new, multidisciplinary programs that will foster Global Health research and teaching within and between institutions, to be called Framework Programs for Global Health. Specifically, the objectives of this FOA are (1) to increase interactions and joint activities among investigators already engaged in Global Health teaching and research within a campus and among institutions; (2) to encourage new investigators from diverse faculties and disciplines and new institutions to enter the Global Health field; and (3) to build curricula and develop educational opportunities that will engage the next generation of scientists and health workers to consider careers in Global Health. The activities initiated under this award will create a framework of support for Global Health initiatives within an institution.

Two core activities will be to create an administrative framework to bring multiple schools (engineering, economics, business, law, arts and sciences, communications, public health, medicine, nursing, veterinary sciences, environmental studies, agriculture, and others) together on the topic of Global Health and to develop multidisciplinary Global Health curricula at the undergraduate, graduate, postdoctoral, and/or professional school levels. Each program should leverage and enhance currently funded Global Health projects at the institution, supported by NIH and other sponsors, as well as encourage new training opportunities, collaborations and research areas. To ensure that institutions support the Framework at the highest level, letters from the University President, Provost, or other Institutional Director will be required.

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The purpose of this announcement is to invite applications for U.S. and developing country institutions for programs to provide non-HIV/AIDS infectious disease research training to scientists and health professionals in order to build sustainable research capacity at institutions in low- and middle-income endemic countries. Proposals are requested for innovative, collaborative research training programs that would contribute to the long-term goal of building sustainable research capacity in endemic infectious diseases at developing country institutions. The intent is to harness scientific knowledge and skills to enhance prevention, treatment, and control of infectious diseases causing major morbidity and mortality in developing countries.

The Fogarty International Center (FIC) will support research-training programs that focus on building sustainable infectious disease research capacity at an institution in an endemic developing country. Sustainable research capacity depends on building a critical mass of scientists and health professionals with in-depth scientific expertise and complementary skills that enable the institution to conduct independent, internationally recognized infectious disease research relevant to the health priorities of their countries. FIC will support research-training programs that focus on major endemic or life-threatening emerging infectious diseases and are structured to provide an appropriate variety of short- and long-term training opportunities for participants from developing country institutions within the context of ongoing U.S. research collaborations.

1. Substantially increase the expertise of trainees in relevant laboratory, clinical, epidemiological, social science, or operational and health services research.
2. Fill existing gaps and strengthen the sustainability of endemic infectious disease research training at a specified developing country institution.
3. Expand and equalize collaborative scientific research interactions between U.S. and developing country scientists.
4. Implement strategies that help insure that developing country trainees integrate into their home country institutions and pursue independently supported scientific careers.
5. Enhance the capacity for developing country institutions to provide data for evidence-based decision making related to endemic infectious disease clinical treatment or prevention and control policies in the host developing country.
6. Strengthen the capacity of developing country institutions to compete for research funding.

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New information, communication, and computational technologies have had profound impacts on the practice of science and engineering. Linked to create a comprehensive cyberinfrastructure, the systems, tools, and services emerging from these new technologies are enabling individuals, groups, and organizations to advance research and education in ways that revolutionize who can participate, what they can do, and how they do it. Sustaining this revolution across all areas of science and engineering requires the formation of a workforce with the knowledge and skills needed to design and deploy as well as adopt and apply these cyber-based systems, tools and services over the long-term. The opportunity for such preparation should be available at all stages of formal and informal education, training and professional development, and must be extended to all interested individuals and communities.

• Prepare current and future generations of scientists, engineers, and educators to design and develop as well as adopt and deploy, cyber-based tools and environments for research and learning, both formal and informal.
• Expand and enhance participation in cyberinfrastructure science and engineering activities of diverse groups of people and organizations, with particular emphasis on the inclusion of traditionally underrepresented individuals, institutions, and communities as both creators and users of cyberinfrastructure.

This solicitation seeks two types of project proposals, both aimed at the preparation of a diverse, cyberinfrastructure-savvy science and engineering workforce. One type of proposal, the Demonstration Project, is exploratory in nature and may be somewhat limited in scope and scale. Demonstration Projects have the potential to serve as exemplars to effective larger-scale implementation activities in the future. The other project type, the Implementation Project, is generally larger in scope or scale and draws on prior experience with the activities or the teams proposed. Implementation Projects are expected to deliver sustainable learning and workforce development activities that complement ongoing NSF investment in cyberinfrastructure.

All CI-TEAM projects seek to broaden and diversify the population of individuals and institutions participating in cyberinfrastructure activities specifically and, thereby, science and engineering more generally. Toward that goal, both types of projects consist of collaborations with expertise in multiple disciplines and involve partnerships that support integrated research and learning among diverse organizations including, as appropriate, academic institutions of higher learning, primary and secondary schools, government, industry, professional societies, other not-for-profit organizations, and international partners. Other key features of CI-TEAM projects involve a commitment to: leveraging existing or current development efforts in cyberinfrastructure technologies; open software standards and open educational resources; the integration of research and learning; institutional partnerships; and strategic implementation, management, and evaluation plans. Following merit review of the proposals received, NSF expects to select for support 12 to 15 Demonstration Projects at up to $250,000 total each and 7 to 12 Implementation Projects at up to $1,000,000 total each that together constitute a rich portfolio of cyberinfrastructure-related workforce development activities.

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The objective of the Obesity Nutrition Research Center is to bring together clinical and basic science investigators from relevant disciplines to enhance and extend the effectiveness of research related to the field of obesity, eating disorders, and energy regulation, with clinical and/or translational applications in these areas. A Core Center must be an identifiable unit within a university or medical center or a consortium of cooperating institutions, including an affiliated university. An existing program of excellence in biomedical basic and clinical research in the areas of obesity, eating disorders, and energy regulation is required.

The research base related to obesity can include a focus on behavior, physical activity, energy metabolism, body composition, cell biology, or nutrient metabolism. Other nutritional sciences research may be included if the investigators make use of the same core services as justified by the research base related to obesity. It would be highly desirable that the principal investigator, as well as the applicant institution, have a commitment to the treatment and prevention of obesity. Applicants should consult with NIDDK staff concerning plans for the development of the Center and the organization of the application.

The Obesity Nutrition Research Centers are based on the core concept. Four to six cores are usually included in a center. Cores are defined as shared resources that enhance productivity or in other ways benefit a group of investigators working in the center to accomplish the stated goals of the center. Examples of such resources include biostatistics, imaging, biotechnology, and instrumentation facilities. It is appropriate and may be beneficial to have one or more central themes around which core center research investigations are focused.

Centers are encouraged to include a clinical component. This clinical component can exist as a stand alone core or part of another core such as the administrative core. Besides leading to a better understanding of disease etiology and natural history of disease, clinical components might provide biostatistics support; enhance clinical study design; foster collaboration among researchers; aid in recruitment of subjects for clinical studies; support epidemiological studies; or provide modest funding for tissue, DNA, or serum storage. In addition, a clinical component may more effectively address NIH policies concerning issues of children, women, and ethnic minority participation in clinical studies.

The availability of a clinic population with adequate representation of women and minorities that can be readily utilized by investigators will play a major role in attracting investigators to the field of obesity research and will serve as a resource in the design of pilot and feasibility projects.

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The Chemistry Research Instrumentation and Facilities Program (CRIF) is structured to enable the National Science Foundation's Division of Chemistry to respond to a variety of needs for infrastructure that promotes research and education in areas traditionally supported by the Division (NSF Chemistry Homepage).

The Departmental Multi-User Instrumentation component of CRIF (CRIF:MU) provides funds to universities, colleges, and consortia thereof for the purchase of multi-user instruments. The maximum request is $500,000 for instrumentation. Additional funds may be requested for personnel who are needed to support cyber-enhanced projects.

• CRIF:ID The Instrument Development component of CRIF (CRIF:ID) provides funds for the design and construction of instruments that will enable new chemical measurements or will significantly broaden the use of chemical instrumentation.
• CRIF:CRF Cyberinfrastructure and Research Facilities (CRIF:CRF) provides funds to establish and support either centers for the development of cyber-enabled chemical research, or regional or national instrumentation facilities. Awards in CRIF:CRF range from $300,000-1,200,000/yr for up to five years.

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